Cargando…

Ginkgolide B Inhibits JAM-A, Cx43, and VE-Cadherin Expression and Reduces Monocyte Transmigration in Oxidized LDL-Stimulated Human Umbilical Vein Endothelial Cells

Aim. To investigate the effect of ginkgolide B on junction proteins and the reduction of monocyte migration in oxidized low-density lipoprotein- (ox-LDL-) treated endothelial cells. Methods. Human umbilical vein endothelial cells (HUVECs) were used in the present study. Immunofluorescence and Wester...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Xueqing, Sun, Wenjia, Zhao, Yanyang, Chen, Beidong, Wu, Wei, Bao, Li, Qi, Ruomei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515296/ https://www.ncbi.nlm.nih.gov/pubmed/26246869 http://dx.doi.org/10.1155/2015/907926

Ejemplares similares

Ginkgolide B Reduces LOX-1 Expression by Inhibiting Akt Phosphorylation and Increasing Sirt1 Expression in Oxidized LDL-Stimulated Human Umbilical Vein Endothelial Cells
por: Ma, Lina, et al.
Publicado: (2013)

Ginkgolide B inhibits platelet and monocyte adhesion in TNFα-treated HUVECs under laminar shear stress
por: Zhang, Ming, et al.
Publicado: (2018)

Ginkgolide B Suppresses TLR4-Mediated Inflammatory Response by Inhibiting the Phosphorylation of JAK2/STAT3 and p38 MAPK in High Glucose-Treated HUVECs
por: Chen, Kun, et al.
Publicado: (2017)

VE-Cadherin-Independent Cancer Cell Incorporation into the Vascular Endothelium Precedes Transmigration
por: Hamilla, Susan M., et al.
Publicado: (2014)

Ginkgolide B Reduces Atherogenesis and Vascular Inflammation in ApoE(−/−) Mice
por: Liu, Xiyun, et al.
Publicado: (2012)

ADAM10-Interacting Tetraspanins Tspan5 and Tspan17 Regulate VE-Cadherin Expression and Promote T Lymphocyte Transmigration
por: Reyat, Jasmeet S., et al.
Publicado: (2017)

DU-145 prostate carcinoma cells that selectively transmigrate narrow obstacles express elevated levels of Cx43
por: Szpak, Katarzyna, et al.
Publicado: (2011)

Resveratrol Inhibits MMP3 and MMP9 Expression and Secretion by Suppressing TLR4/NF-κB/STAT3 Activation in Ox-LDL-Treated HUVECs
por: Zhang, Ming, et al.
Publicado: (2019)

Differential Localization of VE- and N-Cadherins in Human Endothelial Cells: VE-Cadherin Competes with N-Cadherin for Junctional Localization
por: Navarro, Pilar, et al.
Publicado: (1998)

How VE-cadherin goes with the flow
por: Short, Ben
Publicado: (2015)

Hyperglycemia aggravates monocyte-endothelial adhesion in human umbilical vein endothelial cells from women with gestational diabetes mellitus by inducing Cx43 overexpression
por: Zhang, Qian, et al.
Publicado: (2021)

N-cadherin acts upstream of VE-cadherin in controlling vascular morphogenesis
por: Luo, Yang, et al.
Publicado: (2005)

Transformation of multi-component ginkgolide into ginkgolide B by Coprinus comatus
por: Ding, HongXue, et al.
Publicado: (2015)

Endothelial Phosphatase VE-PTP Participates in Vasculogenic Mimicry by Preventing Autophagic Degradation of VE-Cadherin
por: Delgado-Bellido, Daniel, et al.
Publicado: (2020)

Endothelial permeability and VE-cadherin: A wacky comradeship
por: Gavard, Julie
Publicado: (2014)

VE-Cadherin Is Required for Lymphatic Valve Formation and Maintenance
por: Yang, Ying, et al.
Publicado: (2019)

Chronic Stress and Gonadectomy Affect the Expression of Cx37, Cx40 and Cx43 in the Spinal Cord
por: Jurić, Marija, et al.
Publicado: (2021)

Comparative Analysis of Cx31 and Cx43 in Differentiation-Competent Rodent Keratinocytes
por: Au, Akina, et al.
Publicado: (2020)

A novel role of Cx43-composed GJIC in PDT phototoxicity: an implication of Cx43 for the enhancement of PDT efficacy
por: Wu, Deng-Pan, et al.
Publicado: (2019)

Biosynthesis pathways of ginkgolides
por: Zeng, Zihan, et al.
Publicado: (2013)

Neuroregulatory role of ginkgolides
por: Gachowska, Martyna, et al.
Publicado: (2021)

A Role for the αvβ3 Integrin in the Transmigration of Monocytes
por: Weerasinghe, Dheepika, et al.
Publicado: (1998)

The selective binding and transmigration of monocytes through the junctional complexes of human endothelium
Publicado: (1988)

Interfering with VE-PTP stabilizes endothelial junctions in vivo via Tie-2 in the absence of VE-cadherin
por: Frye, Maike, et al.
Publicado: (2015)

VE-PTP stabilizes VE-cadherin junctions and the endothelial barrier via a phosphatase-independent mechanism
por: Juettner, Vanessa V., et al.
Publicado: (2019)

Endothelial barrier dysfunction in systemic inflammation is mediated by soluble VE-cadherin interfering VE-PTP signaling
por: Knop, Juna-Lisa, et al.
Publicado: (2023)

Correlations of Differentially Expressed Gap Junction Connexins Cx26, Cx30, Cx32, Cx43 and Cx46 with Breast Cancer Progression and Prognosis
por: Teleki, Ivett, et al.
Publicado: (2014)

Electrophysiology of Single and Aggregate Cx43 Hemichannels
por: Brokamp, Cole, et al.
Publicado: (2012)

Importance of Cx43 for Right Ventricular Function
por: Boengler, Kerstin, et al.
Publicado: (2021)

The Interplay of Cx26, Cx32, Cx37, Cx40, Cx43, Cx45, and Panx1 in Inner-Ear Development of Yotari (dab1−/−) Mice and Humans
por: Lesko, Josip, et al.
Publicado: (2022)

VE-Cadherin–Mediated Epigenetic Regulation of Endothelial Gene Expression
por: Morini, Marco F., et al.
Publicado: (2018)

Antitumor immunity induced by VE-cadherin modified DC vaccine
por: Zhou, Jing, et al.
Publicado: (2017)

Mechanisms Ensuring Endothelial Junction Integrity Beyond VE-Cadherin
por: Duong, Cao Nguyen, et al.
Publicado: (2020)

Extracellular matrix regulates force transduction at VE-cadherin junctions
por: Kong, Xinyu, et al.
Publicado: (2022)

Targeting Cx43 and N-Cadherin, Which Are Abnormally Upregulated in Venous Leg Ulcers, Influences Migration, Adhesion and Activation of Rho GTPases
por: Mendoza-Naranjo, Ariadna, et al.
Publicado: (2012)

VE-PTP maintains the endothelial barrier via plakoglobin and becomes dissociated from VE-cadherin by leukocytes and by VEGF
por: Nottebaum, Astrid F., et al.
Publicado: (2008)

Dissociation of VE-PTP from VE-cadherin is required for leukocyte extravasation and for VEGF-induced vascular permeability in vivo
por: Broermann, Andre, et al.
Publicado: (2011)

Water-Soluble Tomato Extract Fruitflow Alters the Phosphoproteomic Profile of Collagen-Stimulated Platelets
por: Zhang, Shenghao, et al.
Publicado: (2021)

Opposite Effects of Moderate and Extreme Cx43 Deficiency in Conditional Cx43-Deficient Mice on Angiotensin II-Induced Cardiac Fibrosis
por: Valls-Lacalle, Laura, et al.
Publicado: (2019)

Monocyte-selective transendothelial migration: dissection of the binding and transmigration phases by an in vitro assay
Publicado: (1992)

Cannot write session to /tmp/vufind_sessions/sess_tq51hcr5u41b8guehf97u3el9r