Umbilical Cord Tissue-Derived Cells as Therapeutic Agents

Although the characteristics of SC, including UC-derived cells, are a dramatically discussed issue, this review will focus particularly on some controversial issues regarding clinical utility of cells isolated from UC tissue. UC-derived cells have several advantages compared to other types and sourc...

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Detalles Bibliográficos
Autores principales: Maslova, Olga, Novak, Miroslav, Kruzliak, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515303/
https://www.ncbi.nlm.nih.gov/pubmed/26246808
http://dx.doi.org/10.1155/2015/150609
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author Maslova, Olga
Novak, Miroslav
Kruzliak, Peter
author_facet Maslova, Olga
Novak, Miroslav
Kruzliak, Peter
author_sort Maslova, Olga
collection PubMed
description Although the characteristics of SC, including UC-derived cells, are a dramatically discussed issue, this review will focus particularly on some controversial issues regarding clinical utility of cells isolated from UC tissue. UC-derived cells have several advantages compared to other types and sources of stem cells. The impact of UC topography on cell characteristics is briefly discussed. The necessity to adapt existing methods of cell isolation and culturing to GMP conditions is mentioned, as well as possible cryopreservation of this material. Light is shed on some future perspectives for UC-derived cells.
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spelling pubmed-45153032015-08-05 Umbilical Cord Tissue-Derived Cells as Therapeutic Agents Maslova, Olga Novak, Miroslav Kruzliak, Peter Stem Cells Int Review Article Although the characteristics of SC, including UC-derived cells, are a dramatically discussed issue, this review will focus particularly on some controversial issues regarding clinical utility of cells isolated from UC tissue. UC-derived cells have several advantages compared to other types and sources of stem cells. The impact of UC topography on cell characteristics is briefly discussed. The necessity to adapt existing methods of cell isolation and culturing to GMP conditions is mentioned, as well as possible cryopreservation of this material. Light is shed on some future perspectives for UC-derived cells. Hindawi Publishing Corporation 2015 2015-07-12 /pmc/articles/PMC4515303/ /pubmed/26246808 http://dx.doi.org/10.1155/2015/150609 Text en Copyright © 2015 Olga Maslova et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Maslova, Olga
Novak, Miroslav
Kruzliak, Peter
Umbilical Cord Tissue-Derived Cells as Therapeutic Agents
title Umbilical Cord Tissue-Derived Cells as Therapeutic Agents
title_full Umbilical Cord Tissue-Derived Cells as Therapeutic Agents
title_fullStr Umbilical Cord Tissue-Derived Cells as Therapeutic Agents
title_full_unstemmed Umbilical Cord Tissue-Derived Cells as Therapeutic Agents
title_short Umbilical Cord Tissue-Derived Cells as Therapeutic Agents
title_sort umbilical cord tissue-derived cells as therapeutic agents
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515303/
https://www.ncbi.nlm.nih.gov/pubmed/26246808
http://dx.doi.org/10.1155/2015/150609
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AT novakmiroslav umbilicalcordtissuederivedcellsastherapeuticagents
AT kruzliakpeter umbilicalcordtissuederivedcellsastherapeuticagents

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