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The Etiology and Clinical Evaluations of Neonatal Seizures in Kashan, IRAN

OBJECTIVE: Detection of seizure, its etiology, and clinical types is important for guiding therapy. This study was designed to evaluate the etiology and clinical evaluations of neonatal seizures in Kashan, Iran. MATERIALS AND METHODS: The data of 100 hospitalized neonates with a complaint of seizure...

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Autores principales: TALEBIAN, Ahmad, JAHANGIRI, Mohammad, RABIEE, Mahin, MASOUDI ALAVI, Negin, AKBARI, Hossein, SADAT, Zohreh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shahid Beheshti University of Medical Sciences 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515338/
https://www.ncbi.nlm.nih.gov/pubmed/26221160
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author TALEBIAN, Ahmad
JAHANGIRI, Mohammad
RABIEE, Mahin
MASOUDI ALAVI, Negin
AKBARI, Hossein
SADAT, Zohreh
author_facet TALEBIAN, Ahmad
JAHANGIRI, Mohammad
RABIEE, Mahin
MASOUDI ALAVI, Negin
AKBARI, Hossein
SADAT, Zohreh
author_sort TALEBIAN, Ahmad
collection PubMed
description OBJECTIVE: Detection of seizure, its etiology, and clinical types is important for guiding therapy. This study was designed to evaluate the etiology and clinical evaluations of neonatal seizures in Kashan, Iran. MATERIALS AND METHODS: The data of 100 hospitalized neonates with a complaint of seizures in Kashan City, from January 2006 to January 2011 were evaluated. The pediatric neurologist made the final diagnosis. The gestational age, neonate admission age, type of delivery, and laboratory and radiological investigations were reviewed from the medical records. The relation of seizure etiology and other variables were compared using the Chi-square test. All the statistical analyses were performed using SPSS (ver 11.5). RESULTS: A total of 100 neonates were hospitalized with a diagnosis of seizures. The overall incidence rate of seizures was 2.6 per 1,000 live births. A total of 59% of seizures happened in the first three days of life. The etiologies of seizures were hypoxicischemic encephalopathy (HIE) (36%), hyponatremia (12%), hypoglycemia (11%), intracranial hemorrhage (11%), infections (10%), hypocalcemia (8%), metabolic disorders (7%), the structural anomalies (5%), and hypomagnesaemia (4%). In 23% of neonates, no specific etiology was found and 23% had multiple etiologies. In 45% of neonates, the EEG was not recorded. The type of the seizures were focal-clonic (26%), tonic (25%), multifocal clonic (34%), subtle (11%), and myoclonic (4%). The types of the seizure were unrelated to the paraclinical findings. CONCLUSION: Neonatal seizures are common and HIE was the main cause of seizures in this study. The clinical evaluation of neonatal seizures needs improvement.
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spelling pubmed-45153382015-07-28 The Etiology and Clinical Evaluations of Neonatal Seizures in Kashan, IRAN TALEBIAN, Ahmad JAHANGIRI, Mohammad RABIEE, Mahin MASOUDI ALAVI, Negin AKBARI, Hossein SADAT, Zohreh Iran J Child Neurol Original Article OBJECTIVE: Detection of seizure, its etiology, and clinical types is important for guiding therapy. This study was designed to evaluate the etiology and clinical evaluations of neonatal seizures in Kashan, Iran. MATERIALS AND METHODS: The data of 100 hospitalized neonates with a complaint of seizures in Kashan City, from January 2006 to January 2011 were evaluated. The pediatric neurologist made the final diagnosis. The gestational age, neonate admission age, type of delivery, and laboratory and radiological investigations were reviewed from the medical records. The relation of seizure etiology and other variables were compared using the Chi-square test. All the statistical analyses were performed using SPSS (ver 11.5). RESULTS: A total of 100 neonates were hospitalized with a diagnosis of seizures. The overall incidence rate of seizures was 2.6 per 1,000 live births. A total of 59% of seizures happened in the first three days of life. The etiologies of seizures were hypoxicischemic encephalopathy (HIE) (36%), hyponatremia (12%), hypoglycemia (11%), intracranial hemorrhage (11%), infections (10%), hypocalcemia (8%), metabolic disorders (7%), the structural anomalies (5%), and hypomagnesaemia (4%). In 23% of neonates, no specific etiology was found and 23% had multiple etiologies. In 45% of neonates, the EEG was not recorded. The type of the seizures were focal-clonic (26%), tonic (25%), multifocal clonic (34%), subtle (11%), and myoclonic (4%). The types of the seizure were unrelated to the paraclinical findings. CONCLUSION: Neonatal seizures are common and HIE was the main cause of seizures in this study. The clinical evaluation of neonatal seizures needs improvement. Shahid Beheshti University of Medical Sciences 2015 /pmc/articles/PMC4515338/ /pubmed/26221160 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
TALEBIAN, Ahmad
JAHANGIRI, Mohammad
RABIEE, Mahin
MASOUDI ALAVI, Negin
AKBARI, Hossein
SADAT, Zohreh
The Etiology and Clinical Evaluations of Neonatal Seizures in Kashan, IRAN
title The Etiology and Clinical Evaluations of Neonatal Seizures in Kashan, IRAN
title_full The Etiology and Clinical Evaluations of Neonatal Seizures in Kashan, IRAN
title_fullStr The Etiology and Clinical Evaluations of Neonatal Seizures in Kashan, IRAN
title_full_unstemmed The Etiology and Clinical Evaluations of Neonatal Seizures in Kashan, IRAN
title_short The Etiology and Clinical Evaluations of Neonatal Seizures in Kashan, IRAN
title_sort etiology and clinical evaluations of neonatal seizures in kashan, iran
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515338/
https://www.ncbi.nlm.nih.gov/pubmed/26221160
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