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Assessing the Impact of Mechanical Damage on Full-Thickness Porcine and Human Skin Using an In Vitro Approach
For most xenobiotics, the rates of percutaneous absorption are limited by diffusion through the horny layer of skin. However, percutaneous absorption of chemicals may seriously increase when the skin is damaged. The aim of this work was to develop an in vitro representative model of mechanically dam...
Autores principales: | Dabboue, Hinda, Builles, Nicolas, Frouin, Éric, Scott, Dan, Ramos, Jeanne, Marti-Mestres, Gilberte |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515495/ https://www.ncbi.nlm.nih.gov/pubmed/26247021 http://dx.doi.org/10.1155/2015/434623 |
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