Marine Bromophenol Derivative 3,4-Dibromo-5-(2-bromo-3,4-dihydroxy-6-isopropoxymethyl benzyl)benzene-1,2-diol Protects Hepatocytes from Lipid-Induced Cell Damage and Insulin Resistance via PTP1B Inhibition

3,4-Dibromo-5-(2-bromo-3,4-dihydroxy-6-isopropoxymethyl benzyl)benzene-1,2-diol (HPN) is a bromophenol derivative from the marine red alga Rhodomela confervoides. We have previously found that HPN exerted an anti-hyperglycemic property in db/db mouse model. In the present study, we found that HPN co...

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Detalles Bibliográficos
Autores principales: Luo, Jiao, Wu, Ning, Jiang, Bo, Wang, Lijun, Wang, Shuaiyu, Li, Xiangqian, Wang, Baocheng, Wang, Changhui, Shi, Dayong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515627/
https://www.ncbi.nlm.nih.gov/pubmed/26193288
http://dx.doi.org/10.3390/md13074452

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