The AhR Ligand, TCDD, Regulates Androgen Receptor Activity Differently in Androgen-Sensitive versus Castration-Resistant Human Prostate Cancer Cells

The reported biological effects of TCDD include induction of drug metabolizing enzymes, wasting syndrome and tumor promotion. TCDD elicits most of its effects through binding the aryl hydrocarbon receptor (AhR). TCDD induced degradation of AhR has been widely reported and requires ubiquitination of...

Descripción completa

Detalles Bibliográficos
Autores principales: Ghotbaddini, Maryam, Powell, Joann B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515671/
https://www.ncbi.nlm.nih.gov/pubmed/26154658
http://dx.doi.org/10.3390/ijerph120707506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515671/
https://www.ncbi.nlm.nih.gov/pubmed/26154658
http://dx.doi.org/10.3390/ijerph120707506

Ejemplares similares