DNA-PKcs Negatively Regulates Cyclin B1 Protein Stability through Facilitating Its Ubiquitination Mediated by Cdh1-APC/C Pathway

The catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) is a critical component of the non-homologous end-joining pathway of DNA double-stranded break repair. DNA-PKcs has also been shown recently functioning in mitotic regulation. Here, we report that DNA-PKcs negatively regulates the stab...

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Detalles Bibliográficos
Autores principales: Shang, Zeng-Fu, Tan, Wei, Liu, Xiao-Dan, Yu, Lan, Li, Bing, Li, Ming, Song, Man, Wang, Yu, Xiao, Bei-Bei, Zhong, Cai-Gao, Guan, Hua, Zhou, Ping-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515814/
https://www.ncbi.nlm.nih.gov/pubmed/26221070
http://dx.doi.org/10.7150/ijbs.12443

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