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Norisoboldine, an Anti-Arthritis Alkaloid Isolated from Radix Linderae, Attenuates Osteoclast Differentiation and Inflammatory Bone Erosion in an Aryl Hydrocarbon Receptor-Dependent Manner
Norisoboldine (NOR), the primary isoquinoline alkaloid constituent of the root of Lindera aggregata, has previously been demonstrated to attenuate osteoclast (OC) differentiation. Accumulative evidence has shown that aryl hydrocarbon receptor (AhR) plays an important role in regulating the different...
Autores principales: | Wei, Zhi-feng, Lv, Qi, Xia, Ying, Yue, Meng-fan, Shi, Can, Xia, Yu-feng, Chou, Gui-xin, Wang, Zheng-tao, Dai, Yue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515821/ https://www.ncbi.nlm.nih.gov/pubmed/26221077 http://dx.doi.org/10.7150/ijbs.12152 |
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