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Attenuated Semliki Forest virus for cancer treatment in dogs: safety assessment in two laboratory Beagles

BACKGROUND: Dogs suffer from spontaneous tumors which may be amenable to therapies developed for human cancer patients, and dogs may serve as large-animal cancer models. A non-pathogenic Semliki Forest virus vector VA7-EGFP previously showed promise in targeting human tumor xenografts in mice, but t...

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Detalles Bibliográficos
Autores principales:	Autio, Karoliina P. M., Ruotsalainen, Janne J., Anttila, Marjukka O., Niittykoski, Minna, Waris, Matti, Hemminki, Akseli, Vähä-Koskela, Markus J. V., Hinkkanen, Ari E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515883/ https://www.ncbi.nlm.nih.gov/pubmed/26215394 http://dx.doi.org/10.1186/s12917-015-0498-2

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