A review of the re-emergence of adrenocorticotrophic hormone therapy in glomerular disease, more than a drug of last resort?

There has been a re-emergence of interest in adrenocorticotropic hormone (ACTH) in patients with resistant nephrotic syndrome. We describe a patient with severe nephrosis and advanced chronic kidney disease with idiopathic membranous nephropathy resistant to conventional immunosuppressive therapies...

Descripción completa

Detalles Bibliográficos
Autores principales: Goldsmith, Christopher J., Hammad, Salim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Contents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515901/
https://www.ncbi.nlm.nih.gov/pubmed/26251711
http://dx.doi.org/10.1093/ckj/sfv046
_version_ 1782382986228924416
author Goldsmith, Christopher J.
Hammad, Salim
author_facet Goldsmith, Christopher J.
Hammad, Salim
author_sort Goldsmith, Christopher J.
collection PubMed
description There has been a re-emergence of interest in adrenocorticotropic hormone (ACTH) in patients with resistant nephrotic syndrome. We describe a patient with severe nephrosis and advanced chronic kidney disease with idiopathic membranous nephropathy resistant to conventional immunosuppressive therapies that achieved lasting remission with ACTH therapy. We explore the literature showing the extra renoprotective effects which might explain the response of proteinuric renal diseases to this treatment.
format Online
Article
Text
id pubmed-4515901
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-45159012015-08-06 A review of the re-emergence of adrenocorticotrophic hormone therapy in glomerular disease, more than a drug of last resort? Goldsmith, Christopher J. Hammad, Salim Clin Kidney J Contents There has been a re-emergence of interest in adrenocorticotropic hormone (ACTH) in patients with resistant nephrotic syndrome. We describe a patient with severe nephrosis and advanced chronic kidney disease with idiopathic membranous nephropathy resistant to conventional immunosuppressive therapies that achieved lasting remission with ACTH therapy. We explore the literature showing the extra renoprotective effects which might explain the response of proteinuric renal diseases to this treatment. Oxford University Press 2015-08 2015-06-17 /pmc/articles/PMC4515901/ /pubmed/26251711 http://dx.doi.org/10.1093/ckj/sfv046 Text en © The Author 2015. Published by Oxford University Press on behalf of ERA-EDTA. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Contents
Goldsmith, Christopher J.
Hammad, Salim
A review of the re-emergence of adrenocorticotrophic hormone therapy in glomerular disease, more than a drug of last resort?
title A review of the re-emergence of adrenocorticotrophic hormone therapy in glomerular disease, more than a drug of last resort?
title_full A review of the re-emergence of adrenocorticotrophic hormone therapy in glomerular disease, more than a drug of last resort?
title_fullStr A review of the re-emergence of adrenocorticotrophic hormone therapy in glomerular disease, more than a drug of last resort?
title_full_unstemmed A review of the re-emergence of adrenocorticotrophic hormone therapy in glomerular disease, more than a drug of last resort?
title_short A review of the re-emergence of adrenocorticotrophic hormone therapy in glomerular disease, more than a drug of last resort?
title_sort review of the re-emergence of adrenocorticotrophic hormone therapy in glomerular disease, more than a drug of last resort?
topic Contents
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515901/
https://www.ncbi.nlm.nih.gov/pubmed/26251711
http://dx.doi.org/10.1093/ckj/sfv046
work_keys_str_mv AT goldsmithchristopherj areviewofthereemergenceofadrenocorticotrophichormonetherapyinglomerulardiseasemorethanadrugoflastresort
AT hammadsalim areviewofthereemergenceofadrenocorticotrophichormonetherapyinglomerulardiseasemorethanadrugoflastresort
AT goldsmithchristopherj reviewofthereemergenceofadrenocorticotrophichormonetherapyinglomerulardiseasemorethanadrugoflastresort
AT hammadsalim reviewofthereemergenceofadrenocorticotrophichormonetherapyinglomerulardiseasemorethanadrugoflastresort

Ejemplares similares