Non-Heart-Beating Donor Heart Transplantation: Breaking the Taboo

Roughly 60% of hearts offered for transplantation are rejected because of organ dysfunction. Moreover, hearts from circulatory-dead patients have long been thought to be non-amenable for transplantation, unlike other organs. However, tentative surgical attempts inspired by the knowledge obtained fro...

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Detalles Bibliográficos
Autores principales: Fatullayev, Javid, Samak, Mostafa, Sabashnikov, Anton, Weymann, Alexander, Mohite, Prashant N., García-Sáez, Diana, Patil, Nikhil P., Dohmen, Pascal M., Popov, Aron-Frederik, Simon, André R., Zeriouh, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2015
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515934/
https://www.ncbi.nlm.nih.gov/pubmed/26174972
http://dx.doi.org/10.12659/MSMBR.894985
Descripción
Sumario:Roughly 60% of hearts offered for transplantation are rejected because of organ dysfunction. Moreover, hearts from circulatory-dead patients have long been thought to be non-amenable for transplantation, unlike other organs. However, tentative surgical attempts inspired by the knowledge obtained from preclinical research to recover those hearts have been performed, finally culminating in clinically successful transplants. In this review we sought to address the major concerns in non-heart-beating donor heart transplantation and highlight recently introduced developments to overcome them.

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