TUT7 controls the fate of precursor microRNAs by using three different uridylation mechanisms

Terminal uridylyl transferases (TUTs) function as integral regulators of microRNA (miRNA) biogenesis. Using biochemistry, single-molecule, and deep sequencing techniques, we here investigate the mechanism by which human TUT7 (also known as ZCCHC6) recognizes and uridylates precursor miRNAs (pre-miRN...

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Detalles Bibliográficos
Autores principales: Kim, Boseon, Ha, Minju, Loeff, Luuk, Chang, Hyeshik, Simanshu, Dhirendra K, Li, Sisi, Fareh, Mohamed, Patel, Dinshaw J, Joo, Chirlmin, Kim, V Narry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516432/
https://www.ncbi.nlm.nih.gov/pubmed/25979828
http://dx.doi.org/10.15252/embj.201590931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516432/
https://www.ncbi.nlm.nih.gov/pubmed/25979828
http://dx.doi.org/10.15252/embj.201590931

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