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TUT7 controls the fate of precursor microRNAs by using three different uridylation mechanisms
Terminal uridylyl transferases (TUTs) function as integral regulators of microRNA (miRNA) biogenesis. Using biochemistry, single-molecule, and deep sequencing techniques, we here investigate the mechanism by which human TUT7 (also known as ZCCHC6) recognizes and uridylates precursor miRNAs (pre-miRN...
Autores principales: | Kim, Boseon, Ha, Minju, Loeff, Luuk, Chang, Hyeshik, Simanshu, Dhirendra K, Li, Sisi, Fareh, Mohamed, Patel, Dinshaw J, Joo, Chirlmin, Kim, V Narry |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516432/ https://www.ncbi.nlm.nih.gov/pubmed/25979828 http://dx.doi.org/10.15252/embj.201590931 |
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