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H(2)O(2)-induced Ca(2+) influx and its inhibition by N-(p-amylcinnamoyl) anthranilic acid in the β-cells: involvement of TRPM2 channels

Type 2 melastatin-related transient receptor potential channel (TRPM2), a member of the melastatin-related TRP (transient receptor potential) subfamily is a Ca(2+)-permeable channel activated by hydrogen peroxide (H(2)O(2)). We have investigated the role of TRPM2 channels in mediating the H(2)O(2)-i...

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Detalles Bibliográficos
Autores principales: Bari, Muhammad R, Akbar, Sanian, Eweida, Mohamed, Kühn, Frank JP, Gustafsson, Amanda Jabin, Lückhoff, Andreas, Islam, Md Shahidul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516483/
https://www.ncbi.nlm.nih.gov/pubmed/19382906
http://dx.doi.org/10.1111/j.1582-4934.2009.00737.x