SIRT1 confers protection against UVB- and H(2)O(2)-induced cell death via modulation of p53 and JNK in cultured skin keratinocytes

SIRT1 is a member of a highly conserved gene family (sirtuins) encoding nicotinamide adenine dinucleotide (NAD)(+)-dependent deacetylases, originally found to deacetylate histones leading to increased DNA stability and prolonged survival in yeast and higher organisms, including mammals. SIRT1 has be...

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Detalles Bibliográficos
Autores principales: Cao, Cong, Lu, Shan, Kivlin, Rebecca, Wallin, Brittany, Card, Elizabeth, Bagdasarian, Andrew, Tamakloe, Tyrone, Wang, Wen-jun, Song, Xiuzu, Chu, Wen-ming, Kouttab, Nicola, Xu, Aie, Wan, Yinsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2009
Materias:
Cell Death
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516512/
https://www.ncbi.nlm.nih.gov/pubmed/18681908
http://dx.doi.org/10.1111/j.1582-4934.2008.00453.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516512/
https://www.ncbi.nlm.nih.gov/pubmed/18681908
http://dx.doi.org/10.1111/j.1582-4934.2008.00453.x

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