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Cyclooxygenase inhibitors repress vascular hyaluronan-synthesis in murine atherosclerosis and neointimal thickening

Hyaluronan (HA) is a key molecule of the extracellular matrix that is thought to be critically involved in both atherosclerosis and restenosis. Recently, it has been demonstrated that the cyclooxygenase (COX) products, prostacyclin and prostaglandin E(2), induce HA synthesis in vitro by transcriptio...

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Detalles Bibliográficos
Autores principales: Marzoll, Andrea, Nagy, Nadine, Wördehoff, Luisa, Dai, Guang, Fries, Susanne, Lindner, Volkhard, Grosser, Tilo, Fischer, Jens W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516520/
https://www.ncbi.nlm.nih.gov/pubmed/19320776
http://dx.doi.org/10.1111/j.1582-4934.2009.00736.x