Let-7 repression leads to HMGA2 overexpression in uterine leiomyosarcoma

Overexpression of HMGA2 is common in uterine leiomyomas (ULM). The expression of HMGA2 in its malignant counterpart – uterine leiomyosarcomas (ULMS) remains undetermined. Recently it has been shown that repression of HMGA2 by microRNA let-7s is a critical molecular regulatory mechanism associated wi...

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Detalles Bibliográficos
Autores principales: Shi, Guizhi, Perle, Mary Ann, Mittal, Khush, Chen, Hua, Zou, Xuanyi, Narita, Masashi, Hernando, Eva, Lee, Peng, Wei, Jian-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2009
Materias:
Molecular Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516537/
https://www.ncbi.nlm.nih.gov/pubmed/19602040
http://dx.doi.org/10.1111/j.1582-4934.2008.00541.x

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