Cargando…

A molecular study of pathways involved in the inhibition of cell proliferation in neuroblastoma B65 cells by the GSK-3 inhibitors lithium and SB-415286

Pharmacological GSK-3 inhibitors are potential drugs for the treatment of neurodegenerative diseases, cancer and diabetes. We examined the antiproliferative effects of two GSK-3 inhibitors, lithium and SB-415286, on B65 neuroblastoma cell line. Treatment of B65 cells with either drug administered se...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pizarro, Javier G, Folch, Jaume, Esparza, José Luis, Jordan, J, Pallàs, Mercè, Camins, Antoni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Ltd 2009
Materias:	Molecular Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516538/ https://www.ncbi.nlm.nih.gov/pubmed/18624766 http://dx.doi.org/10.1111/j.1582-4934.2008.00389.x

Ejemplares similares

Experimental Models for Aging and their Potential for Novel Drug Discovery
por: Folch, Jaume, et al.
Publicado: (2018)

Testing Fmr1(KO) Phenotypes in Response to GSK3 Inhibitors: SB216763 versus AFC03127
por: Westmark, Pamela R., et al.
Publicado: (2021)

Dexibuprofen prevents neurodegeneration and cognitive decline in APPswe/PS1dE9 through multiple signaling pathways
por: Ettcheto, Miren, et al.
Publicado: (2017)

SIRT1 and AROS suppress doxorubicin-induced apoptosis via inhibition of GSK3β activity in neuroblastoma cells
por: Kim, Jeong Woo, et al.
Publicado: (2020)

Yokukansan enhances the proliferation of B65 neuroblastoma
por: Nakatani, Yoshihiko, et al.
Publicado: (2016)

Nordentatin Inhibits Neuroblastoma Cell Proliferation and Migration through Regulation of GSK-3 Pathway
por: Boonyarat, Chantana, et al.
Publicado: (2022)

ALK and GSK3: Shared Features of Neuroblastoma and Neural Crest Cells
por: Gonzalez Malagon, Sandra G, et al.
Publicado: (2018)

Understanding the Role of Hypoxia Inducible Factor During Neuro-degeneration for New Therapeutics Opportunities
por: Merelli, Amalia, et al.
Publicado: (2018)

Lithium and Therapeutic Targeting of GSK-3
por: Snitow, Melinda E., et al.
Publicado: (2021)

Effects of Nutrition on Cognitive Function in Adults with or without Cognitive Impairment: A Systematic Review of Randomized Controlled Clinical Trials
por: Gutierrez, Laia, et al.
Publicado: (2021)

Resveratrol: An Antiaging Drug with Potential Therapeutic Applications in Treating Diseases
por: Camins, Antoni, et al.
Publicado: (2009)

Epigenetic mechanisms underlying cognitive impairment and Alzheimer disease hallmarks in 5XFAD mice
por: Griñán-Ferré, Christian, et al.
Publicado: (2016)

Consensus criteria for sensitive detection of minimal neuroblastoma cells in bone marrow, blood and stem cell preparations by immunocytology and QRT-PCR: recommendations by the International Neuroblastoma Risk Group Task Force
por: Beiske, K, et al.
Publicado: (2009)

Effects of the histone deacetylase inhibitor valproic acid on Notch signalling in human neuroblastoma cells
por: Stockhausen, M-T, et al.
Publicado: (2005)

GSK-3 is an RNA polymerase II phospho-CTD kinase
por: Nieto Moreno, Nicolás, et al.
Publicado: (2020)

International consensus for neuroblastoma molecular diagnostics: report from the International Neuroblastoma Risk Group (INRG) Biology Committee
por: Ambros, P F, et al.
Publicado: (2009)

FHL2 interacts with and acts as a functional repressor of Id2 in human neuroblastoma cells
por: Han, Weidong, et al.
Publicado: (2009)

Low-dose interferon-γ-producing human neuroblastoma cells show reduced proliferation and delayed tumorigenicity
por: Airoldi, I, et al.
Publicado: (2004)

Expression of costimulatory molecules in human neuroblastoma. Evidence that CD40+ neuroblastoma cells undergo apoptosis following interaction with CD40L
por: Airoldi, I, et al.
Publicado: (2003)

The GSK3 kinase inhibitor lithium produces unexpected hyperphosphorylation of β-catenin, a GSK3 substrate, in human glioblastoma cells
por: Abdul, Ata ur Rahman Mohammed, et al.
Publicado: (2017)

Peroxisomal Proliferator-Activated Receptor β/δ Deficiency Induces Cognitive Alterations
por: Espinosa-Jiménez, Triana, et al.
Publicado: (2022)

Involvement of JNK1 in Neuronal Polarization During Brain Development
por: Castro-Torres, Rubén Darío, et al.
Publicado: (2020)

Editorial: The protein kinase GSK3 in neurobiological functions and neuronal disorders
por: Plattner, Florian, et al.
Publicado: (2023)

Acquisition of EMT phenotype in the gefitinib-resistant cells of a head and neck squamous cell carcinoma cell line through Akt/GSK-3β/snail signalling pathway
por: Maseki, S, et al.
Publicado: (2012)

Glycogen Synthase Kinase 3 (GSK3) Inhibitor, SB-216763, Promotes Pluripotency in Mouse Embryonic Stem Cells
por: Kirby, Leslie A., et al.
Publicado: (2012)

Tumour cell contamination of autologous stem cells grafts in high-risk neuroblastoma: the good news?
por: Handgretinger, R, et al.
Publicado: (2003)

p73α isoforms drive opposite transcriptional and post-transcriptional regulation of MYCN expression in neuroblastoma cells
por: Horvilleur, Emilie, et al.
Publicado: (2008)

GSK-3 Inhibition Modulates Metalloproteases in a Model of Lung Inflammation and Fibrosis
por: Cinetto, Francesco, et al.
Publicado: (2021)

NF-κB Signaling Pathway Confers Neuroblastoma Cells Migration and Invasion Ability via the Regulation of CXCR4
por: Zhi, Yunlai, et al.
Publicado: (2014)

Lithium promotes neural precursor cell proliferation: evidence for the involvement of the non-canonical GSK-3β-NF-AT signaling
por: Qu, Zhaoxia, et al.
Publicado: (2011)

Discovery of imidazole-based GSK-3β inhibitors for transdifferentiation of human mesenchymal stem cells to neurons: A potential single-molecule neurotherapeutic foresight
por: Gupta, Varsha, et al.
Publicado: (2022)

Expression of C-terminal deleted p53 isoforms in neuroblastoma
por: Goldschneider, David, et al.
Publicado: (2006)

MON-LB65 Lithium: The Culprit of Multiple Endocrinopathies
por: Yau, Alice, et al.
Publicado: (2020)

Cell Proliferation in Neuroblastoma
por: Stafman, Laura L., et al.
Publicado: (2016)

Current Research Therapeutic Strategies for Alzheimer's Disease Treatment
por: Folch, Jaume, et al.
Publicado: (2016)

Inhibition of GSK3 by lithium, from single molecules to signaling networks
por: Freland, Laure, et al.
Publicado: (2012)

Protein/DNA arrays identify nitric oxide-regulated cis-element and trans-factor activities some of which govern neuroblastoma cell viability
por: Dhakshinamoorthy, Saravanakumar, et al.
Publicado: (2007)

Inhibition of Akt sensitises neuroblastoma cells to gold(III) porphyrin 1a, a novel antitumour drug induced apoptosis and growth inhibition
por: Li, W, et al.
Publicado: (2009)

On the decay of 110Sb, 111Sb, 112Sb, 113Sb and 114Sb
por: Sunier, J W, et al.
Publicado: (1970)

Antiproliferative and apoptotic effect of LY2090314, a GSK-3 inhibitor, in neuroblastoma in vitro
por: Kunnimalaiyaan, Selvi, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_cg29j9c772der5grnqc6odlppr