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Acquired genetic and functional alterations associated with transforming growth factor β type I resistance in Hep3B human hepatocellular carcinoma cell line

During the neoplastic process tumour cells frequently acquire resistance to the antiproliferative signals of transforming growth factor-β (TGF-β). Here we examined a human hepatocellular carcinoma cell line (Hep3B-TS) sensitive to TGF-β signalling, and a derivative line (Hep3B-TR) rendered resistant...

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Detalles Bibliográficos
Autores principales:	Zimonjic, Drazen B, Zhou, Xiaoling, Lee, Ju-Seog, Ullmannova-Benson, Veronika, Tripathi, Veenu, Thorgeirsson, Snorri S, Popescu, Nicholas C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Ltd 2009
Materias:	Molecular Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516545/ https://www.ncbi.nlm.nih.gov/pubmed/19426152 http://dx.doi.org/10.1111/j.1582-4934.2009.00769.x

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