Inhibition of parvalbumin-expressing interneurons results in complex behavioral changes

Reduced expression of the GAD1 gene-encoded 67-kD protein isoform of glutamic acid decarboxylase (GAD67) is a hallmark of the schizophrenia. GAD67 downregulation occurs in multiple interneuronal subpopulations, including the parvalbumin positive (PVALB+) cells. To investigate the role of the PV-posi...

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Detalles Bibliográficos
Autores principales: Brown, Jacquelyn A., Ramikie, Teniel S., Schmidt, Martin J., Báldi, Rita, Garbett, Krassimira, Everheart, Monika G., Warren, Lambert E., Gellért, Levente, Horváth, Szatmár, Patel, Sachin, Mirnics, Károly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516717/
https://www.ncbi.nlm.nih.gov/pubmed/25623945
http://dx.doi.org/10.1038/mp.2014.192

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