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Ion selectivity of the anthrax toxin channel and its effect on protein translocation

Anthrax toxin consists of three ∼85-kD proteins: lethal factor (LF), edema factor (EF), and protective antigen (PA). PA(63) (the 63-kD, C-terminal portion of PA) forms heptameric channels ((PA(63))(7)) in planar phospholipid bilayer membranes that enable the translocation of LF and EF across the mem...

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Detalles Bibliográficos
Autores principales:	Schiffmiller, Aviva, Anderson, Damon, Finkelstein, Alan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2015
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516782/ https://www.ncbi.nlm.nih.gov/pubmed/26170174 http://dx.doi.org/10.1085/jgp.201511388

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