Nuclear factor κB–inducing kinase activation as a mechanism of pancreatic β cell failure in obesity

The nuclear factor κB (NF-κB) pathway is a master regulator of inflammatory processes and is implicated in insulin resistance and pancreatic β cell dysfunction in the metabolic syndrome. Whereas canonical NF-κB signaling is well studied, there is little information on the divergent noncanonical NF-κ...

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Detalles Bibliográficos
Autores principales: Malle, Elisabeth K., Zammit, Nathan W., Walters, Stacey N., Koay, Yen Chin, Wu, Jianmin, Tan, Bernice M., Villanueva, Jeanette E., Brink, Robert, Loudovaris, Tom, Cantley, James, McAlpine, Shelli R., Hesselson, Daniel, Grey, Shane T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516791/
https://www.ncbi.nlm.nih.gov/pubmed/26122662
http://dx.doi.org/10.1084/jem.20150218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516791/
https://www.ncbi.nlm.nih.gov/pubmed/26122662
http://dx.doi.org/10.1084/jem.20150218

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