Cargando…

Basigin is a druggable target for host-oriented antimalarial interventions

Plasmodium falciparum is the parasite responsible for the most lethal form of malaria, an infectious disease that causes a large proportion of childhood deaths and poses a significant barrier to socioeconomic development in many countries. Although antimalarial drugs exist, the repeated emergence an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zenonos, Zenon A., Dummler, Sara K., Müller-Sienerth, Nicole, Chen, Jianzhu, Preiser, Peter R., Rayner, Julian C., Wright, Gavin J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2015
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516795/ https://www.ncbi.nlm.nih.gov/pubmed/26195724 http://dx.doi.org/10.1084/jem.20150032

Ejemplares similares

BASIGIN is a receptor essential for erythrocyte invasion by Plasmodium falciparum
por: Crosnier, Cécile, et al.
Publicado: (2011)

Towards a comprehensive Plasmodium falciparum merozoite cell surface and secreted recombinant protein library
por: Zenonos, Zenon A, et al.
Publicado: (2014)

Barcoding Genetically Distinct Plasmodium falciparum Strains for Comparative Assessment of Fitness and Antimalarial Drug Resistance
por: Carrasquilla, Manuela, et al.
Publicado: (2022)

A Critical Role of Natural Immunoglobulin M in Immediate Defense Against Systemic Bacterial Infection
por: Boes, Marianne, et al.
Publicado: (1998)

The Nlrp3 inflammasome regulates acute graft-versus-host disease
por: Jankovic, Dragana, et al.
Publicado: (2013)

Molecular Adaptation of Borrelia burgdorferi in the Murine Host
por: Liang, Fang Ting, et al.
Publicado: (2002)

NKG2D function protects the host from tumor initiation
por: Smyth, Mark J., et al.
Publicado: (2005)

Eosinophils are part of the granulocyte response in tuberculosis and promote host resistance in mice
por: Bohrer, Andrea C., et al.
Publicado: (2021)

Transformation of Sporozoites into Early Exoerythrocytic Malaria Parasites Does Not Require Host Cells
por: Kaiser, Karine, et al.
Publicado: (2003)

CD24 Expression on T Cells Is Required for Optimal T Cell Proliferation in Lymphopenic Host
por: Li, Ou, et al.
Publicado: (2004)

The innate immune system in host mice targets cells with allogenic mitochondrial DNA
por: Ishikawa, Kaori, et al.
Publicado: (2010)

Defects in Macrophage Recruitment and Host Defense in Mice Lacking the CCR2 Chemokine Receptor
por: Kurihara, Takao, et al.
Publicado: (1997)

INDUCTION OF A PRIMARY ANTIHAPTEN RESPONSE IN VIVO BY A GRAFT-VS.-HOST REACTION
por: Hamilton, J. A., et al.
Publicado: (1973)

NOD2 regulates hematopoietic cell function during graft-versus-host disease
por: Penack, Olaf, et al.
Publicado: (2009)

PROLIFERATION OF DONOR MARROW AND THYMUS CELLS IN THE MYELOID AND LYMPHOID ORGANS OF IRRADIATED SYNGENEIC HOST MICE
por: Takada, Akikazu, et al.
Publicado: (1973)

CD4(+)CD25(+) Immunoregulatory T Cells: New Therapeutics for Graft-Versus-Host Disease
por: Cohen, José L., et al.
Publicado: (2002)

Surface Sialic Acids Taken from the Host Allow Trypanosome Survival in Tsetse Fly Vectors
por: Nagamune, Kisaburo, et al.
Publicado: (2004)

Nfil3 is crucial for development of innate lymphoid cells and host protection against intestinal pathogens
por: Geiger, Theresa L., et al.
Publicado: (2014)

Development of an antigen microarray for high throughput monoclonal antibody selection
por: Staudt, Nicole, et al.
Publicado: (2014)

Cytomegalovirus Misleads Its Host by Priming of CD8 T Cells Specific for an Epitope Not Presented in Infected Tissues
por: Holtappels, Rafaela, et al.
Publicado: (2004)

Targeting of B and T lymphocyte associated (BTLA) prevents graft-versus-host disease without global immunosuppression
por: Albring, Jörn C., et al.
Publicado: (2010)

β2-adrenergic signals downregulate the innate immune response and reduce host resistance to viral infection
por: Wieduwild, Elisabeth, et al.
Publicado: (2020)

B1 B Lymphocytes Play a Critical Role in Host Protection against Lymphatic Filarial Parasites
por: Paciorkowski, Natalia, et al.
Publicado: (2000)

Highly Selective Escape from KSHV-mediated Host mRNA Shutoff and Its Implications for Viral Pathogenesis
por: Glaunsinger, Britt, et al.
Publicado: (2004)

De Novo Generated Human Red Blood Cells in Humanized Mice Support Plasmodium falciparum Infection
por: Amaladoss, Anburaj, et al.
Publicado: (2015)

Basigin-2 is the predominant basigin isoform that promotes tumor cell migration and invasion and correlates with poor prognosis in epithelial ovarian cancer
por: Zhao, Shu-Hua, et al.
Publicado: (2013)

No evidence for basigin/CD147 as a direct SARS-CoV-2 spike binding receptor
por: Shilts, Jarrod, et al.
Publicado: (2021)

CD40 Signaling Is Impaired in L. major–infected Macrophages and Is Rescued by a p38MAPK Activator Establishing a Host-protective Memory T Cell Response
por: Awasthi, Amit, et al.
Publicado: (2003)

TGF-β1 maintains suppressor function and Foxp3 expression in CD4(+)CD25(+) regulatory T cells
por: Marie, Julien C., et al.
Publicado: (2005)

Identification of ADAM12 as a Novel Basigin Sheddase
por: Albrechtsen, Reidar, et al.
Publicado: (2019)

Immunohistochemical basigin expression level in thyroid cancer tissues
por: Guo, Wan-Ping, et al.
Publicado: (2020)

C3 PROACTIVATOR CONVERTASE AND ITS MODE OF ACTION
por: Müller-Eberhard, Hans J., et al.
Publicado: (1972)

Degradation of T Cell Receptor (TCR)–CD3-ζ Complexes after Antigenic Stimulation
por: Valitutti, Salvatore, et al.
Publicado: (1997)

Delayed Expulsion of the Nematode Trichinella spiralisIn Mice Lacking the Mucosal Mast Cell–Specific Granule Chymase, Mouse Mast Cell Protease-1
por: Knight, Pamela A., et al.
Publicado: (2000)

Somatic Hypermutation in the Absence of DNA-Dependent Protein Kinase Catalytic Subunit (DNA-Pk(cs)) or Recombination-Activating Gene (Rag)1 Activity
por: Bemark, Mats, et al.
Publicado: (2000)

Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies
por: Wright, Katherine E., et al.
Publicado: (2014)

Important Functional Roles of Basigin in Thymocyte Development and T cell Activation
por: Yao, Hui, et al.
Publicado: (2013)

Targeting PfRh5 on Merozoites to Prevent Basigin Binding
por: Papadopoulos, Konstantinos
Publicado: (2012)

CD147/Basigin: a Warburg oncogene in hepatocellular carcinoma?
por: Calvisi, Diego Francesco
Publicado: (2016)

Basigin deficiency prevents anaplerosis and ameliorates insulin resistance and hepatosteatosis
por: Ryuge, Akihiro, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_f42ocnvapv4he9h24mqu9jqp9l