CHMP5 controls bone turnover rates by dampening NF-κB activity in osteoclasts

Physiological bone remodeling requires that bone formation by osteoblasts be tightly coupled to bone resorption by osteoclasts. However, relatively little is understood about how this coupling is regulated. Here, we demonstrate that modulation of NF-κB signaling in osteoclasts via a novel activity o...

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Detalles Bibliográficos
Autores principales: Greenblatt, Matthew B., Park, Kwang Hwan, Oh, Hwanhee, Kim, Jung-Min, Shin, Dong Yeon, Lee, Jae Myun, Lee, Jin Woo, Singh, Anju, Lee, Ki-young, Hu, Dorothy, Xiao, Changchun, Charles, Julia F., Penninger, Josef M., Lotinun, Sutada, Baron, Roland, Ghosh, Sankar, Shim, Jae-Hyuck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516796/
https://www.ncbi.nlm.nih.gov/pubmed/26195726
http://dx.doi.org/10.1084/jem.20150407

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