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Blocking neutrophil diapedesis prevents hemorrhage during thrombocytopenia
Spontaneous organ hemorrhage is the major complication in thrombocytopenia with a potential fatal outcome. However, the exact mechanisms regulating vascular integrity are still unknown. Here, we demonstrate that neutrophils recruited to inflammatory sites are the cellular culprits inducing thrombocy...
Autores principales: | Hillgruber, Carina, Pöppelmann, Birgit, Weishaupt, Carsten, Steingräber, Annika Kathrin, Wessel, Florian, Berdel, Wolfgang E., Gessner, J. Engelbert, Ho-Tin-Noé, Benoît, Vestweber, Dietmar, Goerge, Tobias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516803/ https://www.ncbi.nlm.nih.gov/pubmed/26169941 http://dx.doi.org/10.1084/jem.20142076 |
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