Cargando…
Double strand break repair by capture of retrotransposon sequences and reverse-transcribed spliced mRNA sequences in mouse zygotes
The CRISPR/Cas system efficiently introduces double strand breaks (DSBs) at a genomic locus specified by a single guide RNA (sgRNA). The DSBs are subsequently repaired through non-homologous end joining (NHEJ) or homologous recombination (HR). Here, we demonstrate that DSBs introduced into mouse zyg...
Autores principales: | Ono, Ryuichi, Ishii, Masayuki, Fujihara, Yoshitaka, Kitazawa, Moe, Usami, Takako, Kaneko-Ishino, Tomoko, Kanno, Jun, Ikawa, Masahito, Ishino, Fumitoshi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516963/ https://www.ncbi.nlm.nih.gov/pubmed/26216318 http://dx.doi.org/10.1038/srep12281 |
Ejemplares similares
-
The role of genes domesticated from LTR retrotransposons and retroviruses in mammals
por: Kaneko-Ishino, Tomoko, et al.
Publicado: (2012) -
An LTR Retrotransposon-Derived Gene Displays Lineage-Specific Structural and Putative Species-Specific Functional Variations in Eutherians
por: Irie, Masahito, et al.
Publicado: (2016) -
Cognitive Function Related to the Sirh11/Zcchc16 Gene Acquired from an LTR Retrotransposon in Eutherians
por: Irie, Masahito, et al.
Publicado: (2015) -
Mammalian-specific genomic functions: Newly acquired traits generated by genomic imprinting and LTR retrotransposon-derived genes in mammals
por: KANEKO-ISHINO, Tomoko, et al.
Publicado: (2015) -
The role of eutherian‐specific RTL1 in the nervous system and its implications for the Kagami‐Ogata and Temple syndromes
por: Kitazawa, Moe, et al.
Publicado: (2021)