Synthetic RNAs Mimicking Structural Domains in the Foot-and-Mouth Disease Virus Genome Elicit a Broad Innate Immune Response in Porcine Cells Triggered by RIG-I and TLR Activation

The innate immune system is the first line of defense against viral infections. Exploiting innate responses for antiviral, therapeutic and vaccine adjuvation strategies is being extensively explored. We have previously described, the ability of small in vitro RNA transcripts, mimicking the sequence...

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Detalles Bibliográficos
Autores principales: Borrego, Belén, Rodríguez-Pulido, Miguel, Revilla, Concepción, Álvarez, Belén, Sobrino, Francisco, Domínguez, Javier, Sáiz, Margarita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517136/
https://www.ncbi.nlm.nih.gov/pubmed/26193305
http://dx.doi.org/10.3390/v7072807

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