Chemical Synthesis of Burkholderia Lipid A Modified with Glycosyl Phosphodiester-Linked 4-Amino-4-deoxy-β-l-arabinose and Its Immunomodulatory Potential

Modification of the Lipid A phosphates by positively charged appendages is a part of the survival strategy of numerous opportunistic Gram-negative bacteria. The phosphate groups of the cystic fibrosis adapted Burkholderia Lipid A are abundantly esterified by 4-amino-4-deoxy-β-l-arabinose (β-l-Ara4N)...

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Detalles Bibliográficos
Autores principales: Hollaus, Ralph, Ittig, Simon, Hofinger, Andreas, Haegman, Mira, Beyaert, Rudi, Kosma, Paul, Zamyatina, Alla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2015
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517147/
https://www.ncbi.nlm.nih.gov/pubmed/25630448
http://dx.doi.org/10.1002/chem.201406058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517147/
https://www.ncbi.nlm.nih.gov/pubmed/25630448
http://dx.doi.org/10.1002/chem.201406058

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