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Self-Assembly of Disorazole C(1) through a One-Pot Alkyne Metathesis Homodimerization Strategy**

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Alkyne metathesis is increasingly explored as a reliable method to close macrocyclic rings, but there are no prior examples of an alkyne-metathesis-based homodimerization approach to natural products. In this approach to the cytotoxic C(2)-symmetric marine-derived bis(lactone) disorazole C(1), a hig...

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Detalles Bibliográficos
Autores principales:	Ralston, Kevin J, Ramstadius, H Clinton, Brewster, Richard C, Niblock, Helen S, Hulme, Alison N
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2015
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517162/ https://www.ncbi.nlm.nih.gov/pubmed/25926364 http://dx.doi.org/10.1002/anie.201501922

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