Physiologically active hydrogel (in situ gel) of sparfloxacin and its evaluation for ocular retention using gamma scintigraphy

OBJECTIVE: Due to the structure and physiological barrier of eye, only 1% of instilled dose is available for action on the corneal surface. In this work, we developed and evaluated chitosan (pH sensitive) and gellan gum (ion sensitive) in situ gel of sparfloxacin to improve precorneal residence time...

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Detalles Bibliográficos
Autores principales: Gupta, Himanshu, Malik, Aqil, Khar, R. K., Ali, Asgar, Bhatnagar, Aseem, Mittal, Gaurav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517321/
https://www.ncbi.nlm.nih.gov/pubmed/26229353
http://dx.doi.org/10.4103/0975-7406.160015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517321/
https://www.ncbi.nlm.nih.gov/pubmed/26229353
http://dx.doi.org/10.4103/0975-7406.160015

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