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Quantifying the healthcare costs of treating severely bleeding major trauma patients: a national study for England

INTRODUCTION: Severely bleeding trauma patients are a small proportion of the major trauma population but account for 40 % of all trauma deaths. Healthcare resource use and costs are likely to be substantial but have not been fully quantified. Knowledge of costs is essential for developing targeted...

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Autores principales: Campbell, Helen E., Stokes, Elizabeth A., Bargo, Danielle N., Curry, Nicola, Lecky, Fiona E., Edwards, Antoinette, Woodford, Maralyn, Seeney, Frances, Eaglestone, Simon, Brohi, Karim, Gray, Alastair M., Stanworth, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517367/
https://www.ncbi.nlm.nih.gov/pubmed/26148506
http://dx.doi.org/10.1186/s13054-015-0987-5
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author Campbell, Helen E.
Stokes, Elizabeth A.
Bargo, Danielle N.
Curry, Nicola
Lecky, Fiona E.
Edwards, Antoinette
Woodford, Maralyn
Seeney, Frances
Eaglestone, Simon
Brohi, Karim
Gray, Alastair M.
Stanworth, Simon J.
author_facet Campbell, Helen E.
Stokes, Elizabeth A.
Bargo, Danielle N.
Curry, Nicola
Lecky, Fiona E.
Edwards, Antoinette
Woodford, Maralyn
Seeney, Frances
Eaglestone, Simon
Brohi, Karim
Gray, Alastair M.
Stanworth, Simon J.
author_sort Campbell, Helen E.
collection PubMed
description INTRODUCTION: Severely bleeding trauma patients are a small proportion of the major trauma population but account for 40 % of all trauma deaths. Healthcare resource use and costs are likely to be substantial but have not been fully quantified. Knowledge of costs is essential for developing targeted cost reduction strategies, informing health policy, and ensuring the cost-effectiveness of interventions. METHODS: In collaboration with the Trauma Audit Research Network (TARN) detailed patient-level data on in-hospital resource use, extended care at hospital discharge, and readmissions up to 12 months post-injury were collected on 441 consecutive adult major trauma patients with severe bleeding presenting at 22 hospitals (21 in England and one in Wales). Resource use data were costed using national unit costs and mean costs estimated for the cohort and for clinically relevant subgroups. Using nationally available data on trauma presentations in England, patient-level cost estimates were up-scaled to a national level. RESULTS: The mean (95 % confidence interval) total cost of initial hospital inpatient care was £19,770 (£18,177 to £21,364) per patient, of which 62 % was attributable to ventilation, intensive care, and ward stays, 16 % to surgery, and 12 % to blood component transfusion. Nursing home and rehabilitation unit care and re-admissions to hospital increased the cost to £20,591 (£18,924 to £22,257). Costs were significantly higher for more severely injured trauma patients (Injury Severity Score ≥15) and those with blunt injuries. Cost estimates for England were £148,300,000, with over a third of this cost attributable to patients aged 65 years and over. CONCLUSIONS: Severely bleeding major trauma patients are a high cost subgroup of all major trauma patients, and the cost burden is projected to rise further as a consequence of an aging population and as evidence continues to emerge on the benefits of early and simultaneous administration of blood products in pre-specified ratios. The findings from this study provide a previously unreported baseline from which the potential impact of changes to service provision and/or treatment practice can begin to be evaluated. Further studies are still required to determine the full costs of post-discharge care requirements, which are also likely to be substantial. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13054-015-0987-5) contains supplementary material, which is available to authorized users.
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spelling pubmed-45173672015-07-29 Quantifying the healthcare costs of treating severely bleeding major trauma patients: a national study for England Campbell, Helen E. Stokes, Elizabeth A. Bargo, Danielle N. Curry, Nicola Lecky, Fiona E. Edwards, Antoinette Woodford, Maralyn Seeney, Frances Eaglestone, Simon Brohi, Karim Gray, Alastair M. Stanworth, Simon J. Crit Care Research INTRODUCTION: Severely bleeding trauma patients are a small proportion of the major trauma population but account for 40 % of all trauma deaths. Healthcare resource use and costs are likely to be substantial but have not been fully quantified. Knowledge of costs is essential for developing targeted cost reduction strategies, informing health policy, and ensuring the cost-effectiveness of interventions. METHODS: In collaboration with the Trauma Audit Research Network (TARN) detailed patient-level data on in-hospital resource use, extended care at hospital discharge, and readmissions up to 12 months post-injury were collected on 441 consecutive adult major trauma patients with severe bleeding presenting at 22 hospitals (21 in England and one in Wales). Resource use data were costed using national unit costs and mean costs estimated for the cohort and for clinically relevant subgroups. Using nationally available data on trauma presentations in England, patient-level cost estimates were up-scaled to a national level. RESULTS: The mean (95 % confidence interval) total cost of initial hospital inpatient care was £19,770 (£18,177 to £21,364) per patient, of which 62 % was attributable to ventilation, intensive care, and ward stays, 16 % to surgery, and 12 % to blood component transfusion. Nursing home and rehabilitation unit care and re-admissions to hospital increased the cost to £20,591 (£18,924 to £22,257). Costs were significantly higher for more severely injured trauma patients (Injury Severity Score ≥15) and those with blunt injuries. Cost estimates for England were £148,300,000, with over a third of this cost attributable to patients aged 65 years and over. CONCLUSIONS: Severely bleeding major trauma patients are a high cost subgroup of all major trauma patients, and the cost burden is projected to rise further as a consequence of an aging population and as evidence continues to emerge on the benefits of early and simultaneous administration of blood products in pre-specified ratios. The findings from this study provide a previously unreported baseline from which the potential impact of changes to service provision and/or treatment practice can begin to be evaluated. Further studies are still required to determine the full costs of post-discharge care requirements, which are also likely to be substantial. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13054-015-0987-5) contains supplementary material, which is available to authorized users. BioMed Central 2015-07-06 2015 /pmc/articles/PMC4517367/ /pubmed/26148506 http://dx.doi.org/10.1186/s13054-015-0987-5 Text en © Campbell et al. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Campbell, Helen E.
Stokes, Elizabeth A.
Bargo, Danielle N.
Curry, Nicola
Lecky, Fiona E.
Edwards, Antoinette
Woodford, Maralyn
Seeney, Frances
Eaglestone, Simon
Brohi, Karim
Gray, Alastair M.
Stanworth, Simon J.
Quantifying the healthcare costs of treating severely bleeding major trauma patients: a national study for England
title Quantifying the healthcare costs of treating severely bleeding major trauma patients: a national study for England
title_full Quantifying the healthcare costs of treating severely bleeding major trauma patients: a national study for England
title_fullStr Quantifying the healthcare costs of treating severely bleeding major trauma patients: a national study for England
title_full_unstemmed Quantifying the healthcare costs of treating severely bleeding major trauma patients: a national study for England
title_short Quantifying the healthcare costs of treating severely bleeding major trauma patients: a national study for England
title_sort quantifying the healthcare costs of treating severely bleeding major trauma patients: a national study for england
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517367/
https://www.ncbi.nlm.nih.gov/pubmed/26148506
http://dx.doi.org/10.1186/s13054-015-0987-5
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