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IL6 secreted by Ewing sarcoma tumor microenvironment confers anti-apoptotic and cell-disseminating paracrine responses in Ewing sarcoma cells

BACKGROUND: The prognosis of patients with Ewing sarcoma (ES) has improved over the course of the last decades. However, those patients suffering from metastatic and recurrent ES still have only poor chances of survival and require new therapeutic approaches. Interleukin-6 (IL6) is a pleiotropic cyt...

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Detalles Bibliográficos
Autores principales: Lissat, Andrej, Joerschke, Mandy, Shinde, Dheeraj A., Braunschweig, Till, Meier, Angelina, Makowska, Anna, Bortnick, Rachel, Henneke, Philipp, Herget, Georg, Gorr, Thomas A., Kontny, Udo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517368/
https://www.ncbi.nlm.nih.gov/pubmed/26215971
http://dx.doi.org/10.1186/s12885-015-1564-7