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IL6 secreted by Ewing sarcoma tumor microenvironment confers anti-apoptotic and cell-disseminating paracrine responses in Ewing sarcoma cells
BACKGROUND: The prognosis of patients with Ewing sarcoma (ES) has improved over the course of the last decades. However, those patients suffering from metastatic and recurrent ES still have only poor chances of survival and require new therapeutic approaches. Interleukin-6 (IL6) is a pleiotropic cyt...
Autores principales: | Lissat, Andrej, Joerschke, Mandy, Shinde, Dheeraj A., Braunschweig, Till, Meier, Angelina, Makowska, Anna, Bortnick, Rachel, Henneke, Philipp, Herget, Georg, Gorr, Thomas A., Kontny, Udo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517368/ https://www.ncbi.nlm.nih.gov/pubmed/26215971 http://dx.doi.org/10.1186/s12885-015-1564-7 |
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