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Blockade of bone morphogenetic protein signaling potentiates the pro-inflammatory phenotype induced by interleukin-17 and tumor necrosis factor-α combination in rheumatoid synoviocytes
INTRODUCTION: Bone morphogenetic proteins (BMPs) are multifunctional secreted growth factors regulating a broad spectrum of functions in numerous systems. An increased expression and production of specific BMPs have been described in the rheumatoid arthritis (RA) synovium. The aim of this study was...
Autores principales: | Varas, Alberto, Valencia, Jaris, Lavocat, Fabien, Martínez, Víctor G., Thiam, Ndiémé Ndongo, Hidalgo, Laura, Fernández-Sevilla, Lidia M., Sacedón, Rosa, Vicente, Angeles, Miossec, Pierre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517404/ https://www.ncbi.nlm.nih.gov/pubmed/26215036 http://dx.doi.org/10.1186/s13075-015-0710-6 |
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