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One-step biosynthesis of α-ketoisocaproate from l-leucine by an Escherichia coli whole-cell biocatalyst expressing an l-amino acid deaminase from Proteus vulgaris

This work aimed to develop a whole-cell biotransformation process for the production of α-ketoisocaproate from L-leucine. A recombinant Escherichia coli strain was constructed by expressing an L-amino acid deaminase from Proteus vulgaris. To enhance α-ketoisocaproate production, the reaction conditi...

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Detalles Bibliográficos
Autores principales:	Song, Yang, Li, Jianghua, Shin, Hyun-dong, Du, Guocheng, Liu, Long, Chen, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517468/ https://www.ncbi.nlm.nih.gov/pubmed/26217895 http://dx.doi.org/10.1038/srep12614

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