DNA methylation signature in peripheral blood reveals distinct characteristics of human X chromosome numerical aberrations

BACKGROUND: Abnormal sex chromosome numbers in humans are observed in Turner (45,X) and Klinefelter (47,XXY) syndromes. Both syndromes are associated with several clinical phenotypes, whose molecular mechanisms are obscure, and show a range of inter-individual penetrance. In order to understand the...

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Detalles Bibliográficos
Autores principales: Sharma, Amit, Jamil, Muhammad Ahmer, Nuesgen, Nicole, Schreiner, Felix, Priebe, Lutz, Hoffmann, Per, Herns, Stefan, Nöthen, Markus M., Fröhlich, Holger, Oldenburg, Johannes, Woelfle, Joachim, El-Maarri, Osman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517491/
https://www.ncbi.nlm.nih.gov/pubmed/26221191
http://dx.doi.org/10.1186/s13148-015-0112-2

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