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Spread of pathology in amyotrophic lateral sclerosis: assessment of phosphorylated TDP-43 along axonal pathways
INTRODUCTION: The progression of amyotrophic lateral sclerosis (ALS) through the brain has recently been staged using independent neuropathological and neuroimaging modalities. The two schemes tie into the concept of pathological spread through corticofugal axonal transmission that stems from observ...
Autores principales: | Fatima, Manaal, Tan, Rachel, Halliday, Glenda M., Kril, Jillian J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517552/ https://www.ncbi.nlm.nih.gov/pubmed/26216351 http://dx.doi.org/10.1186/s40478-015-0226-y |
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