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Amyloid-β ((25-35)) Modulates the Expression of GirK and KCNQ Channel Genes in the Hippocampus
During early stages of Alzheimer’s disease (AD), synaptic dysfunction induced by toxic amyloid-β (Aβ) is present before the accumulation of histopathological hallmarks of the disease. This scenario produces impaired functioning of neuronal networks, altered patterns of synchronous activity and sever...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517786/ https://www.ncbi.nlm.nih.gov/pubmed/26218288 http://dx.doi.org/10.1371/journal.pone.0134385 |