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Amyloid-β ((25-35)) Modulates the Expression of GirK and KCNQ Channel Genes in the Hippocampus

During early stages of Alzheimer’s disease (AD), synaptic dysfunction induced by toxic amyloid-β (Aβ) is present before the accumulation of histopathological hallmarks of the disease. This scenario produces impaired functioning of neuronal networks, altered patterns of synchronous activity and sever...

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Detalles Bibliográficos
Autores principales: Mayordomo-Cava, Jennifer, Yajeya, Javier, Navarro-López, Juan D., Jiménez-Díaz, Lydia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517786/
https://www.ncbi.nlm.nih.gov/pubmed/26218288
http://dx.doi.org/10.1371/journal.pone.0134385

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