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Crystal Structure of a Thermostable Alanine Racemase from Thermoanaerobacter tengcongensis MB4 Reveals the Role of Gln360 in Substrate Selection

Pyridoxal 5’-phosphate (PLP) dependent alanine racemase catalyzes racemization of L-Ala to D-Ala, a key component of the peptidoglycan network in bacterial cell wall. It has been extensively studied as an important antimicrobial drug target due to its restriction in eukaryotes. However, many markete...

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Detalles Bibliográficos
Autores principales:	Sun, Xiaoliang, He, Guangzheng, Wang, Xiaoyan, Xu, Shujing, Ju, Jiansong, Xu, Xiaoling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517790/ https://www.ncbi.nlm.nih.gov/pubmed/26218070 http://dx.doi.org/10.1371/journal.pone.0133516

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