A Comprehensive Analysis of Replicating Merkel Cell Polyomavirus Genomes Delineates the Viral Transcription Program and Suggests a Role for mcv-miR-M1 in Episomal Persistence

Merkel cell polyomavirus (MCPyV) is considered the etiological agent of Merkel cell carcinoma and persists asymptomatically in the majority of its healthy hosts. Largely due to the lack of appropriate model systems, the mechanisms of viral replication and MCPyV persistence remain poorly understood....

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Detalles Bibliográficos
Autores principales: Theiss, Juliane Marie, Günther, Thomas, Alawi, Malik, Neumann, Friederike, Tessmer, Uwe, Fischer, Nicole, Grundhoff, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517807/
https://www.ncbi.nlm.nih.gov/pubmed/26218535
http://dx.doi.org/10.1371/journal.ppat.1004974

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