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Modification of Gene Expression, Proliferation, and Function of OP9 Stroma Cells by Bcr-Abl-Expressing Leukemia Cells

Expression of the Bcr-Abl fusion gene in hematopoietic progenitor cells (HPCs) results in the development of chronic myelogenous leukemia (CML), for which hematopoietic microenvironment plays an important role. We investigated the specific effects of an HPC line transduced with Bcr-Abl, KOBA, on BM-...

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Detalles Bibliográficos
Autores principales:	Supper, Emmanuelle, Tahir, Suhail, Imai, Takahiko, Inoue, Joe, Minato, Nagahiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517910/ https://www.ncbi.nlm.nih.gov/pubmed/26218064 http://dx.doi.org/10.1371/journal.pone.0134026

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