Towards pathway-centric cancer therapies via pharmacogenomic profiling analysis of ERK signalling pathway

BACKGROUND: Genomic heterogeneity in human cancers complicates gene-centric personalized medicine. Malignant tumors often share a core group of pathways that are perturbed by diverse genetic mutations. Therefore, one possible solution to overcome the heterogeneity challenge is a shift from gene-cent...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Haiyun, Zheng, Xiaoqi, Fei, Teng, Wang, Jinzeng, Li, Xujuan, Liu, Yin, Zhang, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518023/
https://www.ncbi.nlm.nih.gov/pubmed/26220863
http://dx.doi.org/10.1186/s40169-015-0066-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518023/
https://www.ncbi.nlm.nih.gov/pubmed/26220863
http://dx.doi.org/10.1186/s40169-015-0066-1

Ejemplares similares