Cargando…
Identification of a Class of Protein ADP-Ribosylating Sirtuins in Microbial Pathogens
Sirtuins are an ancient family of NAD(+)-dependent deacylases connected with the regulation of fundamental cellular processes including metabolic homeostasis and genome integrity. We show the existence of a hitherto unrecognized class of sirtuins, found predominantly in microbial pathogens. In contr...
Autores principales: | , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518038/ https://www.ncbi.nlm.nih.gov/pubmed/26166706 http://dx.doi.org/10.1016/j.molcel.2015.06.013 |