Identification of a Class of Protein ADP-Ribosylating Sirtuins in Microbial Pathogens

Sirtuins are an ancient family of NAD(+)-dependent deacylases connected with the regulation of fundamental cellular processes including metabolic homeostasis and genome integrity. We show the existence of a hitherto unrecognized class of sirtuins, found predominantly in microbial pathogens. In contr...

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Detalles Bibliográficos
Autores principales: Rack, Johannes Gregor Matthias, Morra, Rosa, Barkauskaite, Eva, Kraehenbuehl, Rolf, Ariza, Antonio, Qu, Yue, Ortmayer, Mary, Leidecker, Orsolya, Cameron, David R., Matic, Ivan, Peleg, Anton Y., Leys, David, Traven, Ana, Ahel, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518038/
https://www.ncbi.nlm.nih.gov/pubmed/26166706
http://dx.doi.org/10.1016/j.molcel.2015.06.013

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