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Crosstalk between monocytes and myometrial smooth muscle in culture generates synergistic pro-inflammatory cytokine production and enhances myocyte contraction, with effects opposed by progesterone

Both term and preterm parturition are characterized by an influx of macrophages and neutrophils into the myometrium and cervix, with co-incident increased peripheral blood monocyte activation. Infection and inflammation are strongly implicated in the pathology of preterm labour (PTL), with progester...

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Detalles Bibliográficos
Autores principales: Rajagopal, S.P., Hutchinson, J.L., Dorward, D.A., Rossi, A.G., Norman, J.E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518137/
https://www.ncbi.nlm.nih.gov/pubmed/26002969
http://dx.doi.org/10.1093/molehr/gav027