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Crosstalk between monocytes and myometrial smooth muscle in culture generates synergistic pro-inflammatory cytokine production and enhances myocyte contraction, with effects opposed by progesterone
Both term and preterm parturition are characterized by an influx of macrophages and neutrophils into the myometrium and cervix, with co-incident increased peripheral blood monocyte activation. Infection and inflammation are strongly implicated in the pathology of preterm labour (PTL), with progester...
Autores principales: | Rajagopal, S.P., Hutchinson, J.L., Dorward, D.A., Rossi, A.G., Norman, J.E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518137/ https://www.ncbi.nlm.nih.gov/pubmed/26002969 http://dx.doi.org/10.1093/molehr/gav027 |
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