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Early Closure of Gastroschisis After Silo Placement Correlates with Earlier Enteral Feeding
Objectives: Gastroschisis is a congenital anomaly affecting 2.3-4.4/10,000 births. Previous studies show initiation of early enteral feeds predicts improved outcomes. We hypothesize that earlier definitive closure after silo placement; can lead to earlier enteral feed initiation. Design/ Setting/ Du...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
EL-MED-Pub
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518187/ https://www.ncbi.nlm.nih.gov/pubmed/26290810 |
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author | Harris, Jamie Poirier, Jennifer Selip, Debra Pillai, Srikumar N. Shah, Ami Jackson, Carl-Christian Chiu, Bill |
author_facet | Harris, Jamie Poirier, Jennifer Selip, Debra Pillai, Srikumar N. Shah, Ami Jackson, Carl-Christian Chiu, Bill |
author_sort | Harris, Jamie |
collection | PubMed |
description | Objectives: Gastroschisis is a congenital anomaly affecting 2.3-4.4/10,000 births. Previous studies show initiation of early enteral feeds predicts improved outcomes. We hypothesize that earlier definitive closure after silo placement; can lead to earlier enteral feed initiation. Design/ Setting/ Duration: Retrospective review of patients with gastroschisis from 2005 and 2014 at a single institution. Material and Methods: The data, including ethnicity, gestational age, birth weight, time to definitive closure, and time of first and full feeds, were analyzed using both Spearman’s rho and the Kruskal-Wallis rank sum test where appropriate; a p value less than 0.05 was considered significant. Results: Forty-three patients (24 males, 19 females) born with gastroschisis were identified. Overall survival rate was 88% (38/43). Forty of the 43 patients had a silo placed prior to definitive closure. Median days to closure were 6 (0 to 85) days. First feeds on average began on day of life (DOL) 17, and full feeds on DOL 25. Earlier closure of gastroschisis correlated with early initiation of feeds (p=0.0001) and shorter time to full feeds (p=0.018), closure by DOL4 showed a trend toward earlier feeding (p=0.13). Conclusion: Earlier closure of gastroschisis after silo placement was associated with earlier feed initiation and shorter time to full feeds. |
format | Online Article Text |
id | pubmed-4518187 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | EL-MED-Pub |
record_format | MEDLINE/PubMed |
spelling | pubmed-45181872015-08-19 Early Closure of Gastroschisis After Silo Placement Correlates with Earlier Enteral Feeding Harris, Jamie Poirier, Jennifer Selip, Debra Pillai, Srikumar N. Shah, Ami Jackson, Carl-Christian Chiu, Bill J Neonatal Surg Original Article Objectives: Gastroschisis is a congenital anomaly affecting 2.3-4.4/10,000 births. Previous studies show initiation of early enteral feeds predicts improved outcomes. We hypothesize that earlier definitive closure after silo placement; can lead to earlier enteral feed initiation. Design/ Setting/ Duration: Retrospective review of patients with gastroschisis from 2005 and 2014 at a single institution. Material and Methods: The data, including ethnicity, gestational age, birth weight, time to definitive closure, and time of first and full feeds, were analyzed using both Spearman’s rho and the Kruskal-Wallis rank sum test where appropriate; a p value less than 0.05 was considered significant. Results: Forty-three patients (24 males, 19 females) born with gastroschisis were identified. Overall survival rate was 88% (38/43). Forty of the 43 patients had a silo placed prior to definitive closure. Median days to closure were 6 (0 to 85) days. First feeds on average began on day of life (DOL) 17, and full feeds on DOL 25. Earlier closure of gastroschisis correlated with early initiation of feeds (p=0.0001) and shorter time to full feeds (p=0.018), closure by DOL4 showed a trend toward earlier feeding (p=0.13). Conclusion: Earlier closure of gastroschisis after silo placement was associated with earlier feed initiation and shorter time to full feeds. EL-MED-Pub 2015-07-01 /pmc/articles/PMC4518187/ /pubmed/26290810 Text en Copyright: © 2015 JNS http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Harris, Jamie Poirier, Jennifer Selip, Debra Pillai, Srikumar N. Shah, Ami Jackson, Carl-Christian Chiu, Bill Early Closure of Gastroschisis After Silo Placement Correlates with Earlier Enteral Feeding |
title | Early Closure of Gastroschisis After Silo Placement Correlates with Earlier Enteral Feeding |
title_full | Early Closure of Gastroschisis After Silo Placement Correlates with Earlier Enteral Feeding |
title_fullStr | Early Closure of Gastroschisis After Silo Placement Correlates with Earlier Enteral Feeding |
title_full_unstemmed | Early Closure of Gastroschisis After Silo Placement Correlates with Earlier Enteral Feeding |
title_short | Early Closure of Gastroschisis After Silo Placement Correlates with Earlier Enteral Feeding |
title_sort | early closure of gastroschisis after silo placement correlates with earlier enteral feeding |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518187/ https://www.ncbi.nlm.nih.gov/pubmed/26290810 |
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