Cargando…
β2-adrenergic signal transduction plays a detrimental role in subchondral bone loss of temporomandibular joint in osteoarthritis
The present study tested whether activation of the sympathetic tone by aberrant joint loading elicits abnormal subchondral bone remodeling in temporomandibular joint (TMJ) osteoarthritis. Abnormal dental occlusion was created in experimental rats, which were then intraperitoneally injected by saline...
Autores principales: | Jiao, Kai, Niu, Li-Na, Li, Qi-hong, Ren, Gao-tong, Zhao, Chang-ming, Liu, Yun-dong, Tay, Franklin R., Wang, Mei-qing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518212/ https://www.ncbi.nlm.nih.gov/pubmed/26219508 http://dx.doi.org/10.1038/srep12593 |
Ejemplares similares
-
Activation of α2A-adrenergic signal transduction in chondrocytes promotes degenerative remodelling of temporomandibular joint
por: Jiao, Kai, et al.
Publicado: (2016) -
Temporomandibular Joint Osteoarthritis: Pathogenic Mechanisms Involving the Cartilage and Subchondral Bone, and Potential Therapeutic Strategies for Joint Regeneration
por: Cardoneanu, Anca, et al.
Publicado: (2022) -
Increased joint loading induces subchondral bone loss of the temporomandibular joint via the RANTES-CCRs-Akt2 axis
por: Feng, Shi-Yang, et al.
Publicado: (2022) -
β2-Adrenergic receptor expression in subchondral bone of patients with varus knee osteoarthritis
por: Yang, Xiaochun, et al.
Publicado: (2022) -
Low frequency pulsed electromagnetic fields exposure alleviate the abnormal subchondral bone remodeling at the early stage of temporomandibular joint osteoarthritis
por: Ma, Yuanjun, et al.
Publicado: (2022)