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Isoliensinine induces apoptosis in triple-negative human breast cancer cells through ROS generation and p38 MAPK/JNK activation
Isoliensinine, liensinine and neferine are major bisbenzylisoquinoline alkaloids in the seed embryo of lotus (Nelumbo nucifera), and exhibit potential anti-cancer activity. Here, we explored the effects of these alkaloids on triple-negative breast cancer cells and found that among the three alkaloid...
Autores principales: | Zhang, Xiyu, Wang, Xiyao, Wu, Tingting, Li, Boxuan, Liu, Tianqi, Wang, Rong, Liu, Qiao, Liu, Zhaojian, Gong, Yaoqin, Shao, Changshun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518223/ https://www.ncbi.nlm.nih.gov/pubmed/26219228 http://dx.doi.org/10.1038/srep12579 |
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